Kathryn is a feminine given name and comes from the Greek meaning for 'pure'. It is a variant of Katherine. It may refer to:

In television and film:

• Kathryn Beaumont (born 1938), English voice actress and school teacher best known for her Disney animation film works
• Kathryn Bernardo (born 1996), Filipina actress and recording artist
• Kathryn Bigelow (born 1951), American film director, first woman to win the Academy Award, BAFTA, and DGA award for Best Director
• Kathryn Busby, American television and film executive
• Kathryn Cressida also known as "Kat" Cressida (born 1968), American voice actress
• Kathryn Crosby (born 1933), American actress and singer who performed her most memorable roles under her birth-name Kathryn Grant
• Kathryn Drysdale (born 1981), English actress
• Kathryn Eames (1908 – 2004), American screen, stage, and television actress
• Kathryn Erbe (born 1966), American actress best known for her lead role as Detective Eames on Law & Order: Criminal Intent
• Kathryn Grayson (1922 – 2010), American lead actress and operatic soprano singer with MGM and Warner Brothers
• Kathryn Hahn (born 1974), American actress best known for her role as Lily Lebowski on Crossing Jordan
• Kathryn Hess (born 1967), American mathematician
• Kathryn Joosten (1939 – 2012), American actress known for roles on The West Wing and Desperate Housewives
• Kathryn Kinley (born 1965), American television personality, journalist and musical theater actress
• Kathryn McGuire (1903 – 1978), American silent-film actress and dancer
• Kathryn Morris (born 1969), American actress best known for her lead role as Detective Lilly Rush on Cold Case
• Kathryn Leigh Scott (born 1943), American television and film actress known for her roles in the soap opera Dark Shadows

In astronomy:

• Kathryn P. Hire (born 1959), American astronaut with over 381 hours in space
• Kathryn Dwyer Sullivan (born 1951), in 1984 became the first American woman to walk in space, and with 532 hours in space
• Kathryn C. Thornton (born 1952), American astronaut with over 975 hours in space

In music:

• Kathryn Calder, Canadian singer-songwriter and member of The New Pornographers
• Kathryn Dawn Lang (k.d. lang) (born 1961), Canadian musician, singer, and songwriter
• Kathryn Roberts, English folk singer
• Kathryn Scott (b. 1974), a singer-songwriter of Contemporary Christian music Northern Ireland
• Kathryn Tickell, (born 1967), English player of the Northumbrian smallpipes and fiddle

In literature:

• Kathryn Deans, Australian children's fantasy author
• Kathryn H. Kidd, Orson Scott Card's co-author in writing a novel named Lovelock
• Kathryn Hulme (1900 – 1981), American author best known for The Nun's Story
• Kathryn Schulz, American freelance writer and journalist
• Kathryn Stockett, American novelist
• Kathryn Tucker Windham (1918 – 2011), American storyteller, author, photographer and journalist

In politics:

• Kathryn I. Bowers (born 1943), American politician and Democratic former member of the Tennessee Senate representing the 33rd district
• Kathryn Garcia (born 1970), Commissioner of the New York City Sanitation Department
• Kathryn E. Granahan née O'Hay (1894 – 1979), American Democratic U.S. Representative from Pennsylvania, 32nd Treasurer of the United States
• Kathryn Hay (born 1975), Tasmanian Labor politician and member of the Tasmanian House of Assembly in the electorate of Bass
• Kathryn O'Loughlin McCarthy née O'Loughlin (1894 – 1952), American Democratic politician and first female U.S. Representative from Kansas

In sports:

• Kathryn Ainsworth, Australian netballer
• Kathryn Binns later became Kathryn Davis (born 1958), English long-distance runner of marathons and half marathon events
• Kathryn Colin "Kathy" Colin (born 1974), American Olympic contender and Pan American Games medalist in canoeing
• Kathryn Teasdale (1964–2016), Canadian auto racing driver

In other fields:

• Kathryn Janeway, fictional Federation starship captain of the USS Voyager in Star Trek: Voyager and admiral in Star Trek: Nemesis
• Kathryn Howard
• Kathryn Mann, mathematician
• Kathryn Paige Harden – American psychologist and behavior geneticist
• Kathryn S. McKinley, American computer scientist
• Kathryn Morgan (born 1988), American ballet dancer
• Kathryn Parsons (born 1982), British tech entrepreneur
• Kathryn Shaw, Canadian theatre actor and director

Events

• Shooting of Kathryn Steinle, a 2015 incident in San Francisco carried out by illegal immigrant Jose Inez Garcia Zarate